bibliografia oil

    • Azzi A et al: RRR-alpha-tocopherol regulation of gene transcription in response to the cell oxidant status. Z Ernahrungswiss. 1998; 37 Suppl 1:21-8.
    • Yu W et al: RRR-alpha-tocopheryl succinate induction of prolonged activation of c-jun amino-terminal kinase and c-jun during induction of apoptosis in human MDA-MB-435 breast cancer cells. Mol Carcinog. 1998 Aug; 22(4):247-57.
    • Stocker A, Zimmer S, Spycher SE, Azzi A: Identification of a novel cytosolic tocopherol-binding protein: structure, specificity, and tissue distribution. IUBMB Life. 1999 Jul; 48(1):49-55.
    • Azzi A et al.: Nonantioxidant functions of alpha-tocopherol in smooth muscle cells. J Nutr. 2001 Feb; 131(2):378S-81S. Review.
    • Neuzil J et al.: Vitamin E analogues as inducers of apoptosis: implications for their potential antineoplastic role. Redox Rep. 2001; 6(3):143-51. Review.
    • Villacorta L et al.: Alpha-tocopherol induces expression of connective tissue growth factor and antagonizes tumor necrosis factor-alpha-mediated down-regulation in human smooth muscle cells. Circ Res. 2003 Jan 10; 92(1):104-10.
    • Rimbach G et al.: Regulation of cell signalling by vitamin E. Proc Nutr Soc. 2002 Nov; 61(4):415-25. Review.
    • Azzi A et al.: The role of alpha-tocopherol in preventing disease: from epidemiology to molecular events. Mol Aspects Med. 2003 Dec; 24(6):325-36. Review.
    • Zingg JM, Azzi A. Non-antioxidant activities of vitamin E. Curr Med Chem. 2004 May;11(9):1113-33. Review.
    • Shun MC et al: Pro-apoptotic mechanisms of action of a novel vitamin E analog (alpha-TEA) and a naturally occurring form of vitamin E (delta-tocotrienol) in MDA-MB-435 human breast cancer cells.

    Nutr Cancer. 2004;48(1):95-105.

    • Zu K, Hawthorn L, Ip C. Up-regulation of c-Jun-NH2-kinase pathway contributes to the induction of mitochondria-mediated apoptosis by alpha-tocopheryl succinate in human prostate cancer cells.

    Mol Cancer Ther. 2005 Jan;4(1):43-50. Azzi A et al: Vitamin E mediates cell signaling and regulation of gene expression. Ann N Y Acad Sci. 2004 Dec; 1031:86-95. Review.

    • Ni J. et al.: Tocopherol-associated protein suppresses prostate cancer cell growth by inhibition of the phosphoinositide 3-kinase pathway. Cancer Res. 2005 Nov 1; 65(21):9807-16.
    • Ahn KS, Sethi G, Krishnan K, Aggarwal BB: Gamma-tocotrienol inhibits nuclear factor-kappaB signaling pathway through inhibition of receptor-interacting protein and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis. J Biol Chem. 2007 Jan 5; 282(1):809-20.
    • Azzi A. Molecular mechanism of alpha-tocopherol action. Free Radic Biol Med. 2007 Jul 1; 43(1):16-21. Review.
    • Zingg JM, Meydani M, Azzi A. alpha-Tocopheryl phosphate—an active lipid mediator? Mol Nutr Food Res. 2010 May;54(5):679-92.
    • Johnson KG, Kornfeld K. The CRAL/TRIO and GOLD domain protein TAP-1 regulates RAF-1 activation. Dev Biol. 2010 May 15;341(2):464-71.
    • Landrier JF et al. Adiponectin expression is induced by vitamin E via a peroxisome proliferator-activated receptor gamma-dependent mechanism. Endocrinology. 2009 Dec;150(12):5318-25.
    • Fang F, Kang Z, Wong C. Vitamin E tocotrienols improve insulin sensitivity through activating peroxisome proliferator-activated receptors. Mol Nutr Food Res. 2010 Mar;54(3):345-52.
    • Kuhad A, Chopra K. Attenuation of diabetic nephropathy by tocotrienol: involvement of NFkB signaling pathway. Life Sci. 2009 Feb 27;84(9-10):296-301.
    • Sena CM et al. Supplementation of coenzyme Q10 and alpha-tocopherol lowers glycated hemoglobin level and lipid peroxidation in pancreas of diabetic rats. Nutr Res. 2008; 28(2):113-21.
    • Whiting PH et al. The relationship between chronic glycaemic control and oxidative stress in type 2 diabetes mellitus. Br J Biomed Sci. 2008;65(2):71-4.
    • Singh I et al. Oxidative stress-induced insulin resistance in skeletal muscle cells is ameliorated by gamma-tocopherol treatment. Eur J Nutr. 2008 Oct;47(7):387-92. Epub 2008 Sep 18.
    • Minamiyama Y et al. Supplementation of alpha-tocopherol improves cardiovascular risk factors via the insulin signalling pathway and reduction of mitochondrial reactive oxygen species in type II diabetic rats. Free Radic Res. 2008 Mar;42(3):261-71.
    • Uusitalo L et al. Serum alpha- and gamma-tocopherol concentrations and risk of advanced beta cell autoimmunity in children with HLA-conferred susceptibility to type 1 diabetes mellitus. Diabetologia 2008 May;51(5):773-80.
    • Fujita K et al. Vitamin E decreases bone mass by stimulating osteoclast fusion. Nat Med. 2012 Mar 4.;10.1038/nm.2659
  • P. Cabras, A. Martelli, Chimica degli Alimenti, Piccin, ISBN 88-299-1696-X
  • Bail, Stuebiger, Krist, Unterweger, Buchbauer, Characterisation of various grape seed oils by volatile compounds, triacylglycerol composition, total phenols and antioxidant capacity in Food Chem., vol. 108, 2008, pp. 1122-1132.
  • Lutterodt, Slavin, Whent, Turner, Yu, Fatty acid composition, oxidative stability, antioxidant and antiproliferative properties of selected cold-pressed grape seed oils and flours in Food Chem., vol. 128, 2011, pp. 391-399.

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